Protein Degraders and Molecular Glues – Part 2

Paid

A new generation of molecules are being developed to disrupt protein-protein interactions and to hijack the cell’s natural machinery for targeted protein degradation. Proteolysis-targeting chimeras (PROTACs), molecular glues, and other modalities are utilizing the ubiquitin-proteasome, lysosome, and autophagy systems to seek out previously “undrugg

27-28 September 2023

Healthcare

Targeting Transcription Factors

Paid

Transcription factors are proteins with DNA-binding domains that are involved in gene transcription. They are key cell regulators and alterations in their structure, binding, or activity are often found associated with many abnormalities in cellular function and in disease. Transcription factors have been targeted in different ways, by modulating t

27-28 September 2023

Healthcare