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A new generation of molecules are being developed to disrupt protein-protein interactions and to hijack the cell’s natural machinery for targeted protein degradation. Proteolysis-targeting chimeras (PROTACs), molecular glues, and other modalities are utilizing the ubiquitin-proteasome, lysosome, and autophagy systems to seek out previously “undruggable” targets for therapeutic intervention. Cambridge Healthtech Institute’s two-part conference on Protein Degraders and Molecular Glues brings together experts from industry and academia to discuss targeted protein degradation as a viable therapeutic approach. Part 1 focuses on emerging assays and screening strategies for new ligases and neosubstrates for targeted degradation. The use of covalent chemistry for inducing chemical proximity and use of AI/ML predictions and modeling to enable targeted protein degradation will also be discussed.
Explore the latest advancements in targeted protein degradation.
The event focuses on emerging assays and screening strategies for new ligases and neosubstrates for targeted degradation. The use of covalent chemistry for inducing chemical proximity and use of AI/ML predictions and modeling to enable targeted protein degradation will also be discussed.
Engage in profound discussions, interact with prominent scientists, researchers, and experts who are driving advancements in this exhilarating field. This immersive experience offers you the opportunity to form valuable connections, exchange innovative ideas, and collaborate with fellow professionals who are at the forefront of research in targeted protein degradation.
Listen to experts who have made significant contributions to the field of targeted protein degradation. Gain inspiration, fresh perspectives, and innovative approaches that can drive your own research and contribute to the development of next-generation therapeutics.
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Cambridge Healthtech Institute – Your Life Science Network Cambridge Healthtech Institute (CHI) is the preeminent life science network for leading researchers and business experts from top pharmaceutical, biotech and academic organizations.
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