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Advancing Therapeutic Discovery and Development: Mechanistic Considerations for Drug DeliveryKeywords: SLC transporters, ABC transporters, nucleic acid vectors, nanoparticles, antibody-based delivery, receptor-mediated transcytosis, cell-based delivery.One of the many challenges in drug discovery and development is the ability to deliver a therapeutic to its site of action at effective concentrations. Over the past several years, new modalities have been designed to ensure successful cell/tissue drug delivery. These paradigms include, but are not limited to, transporters, nucleic acid delivery vehicles, nanoparticles, antibody-based drug conjugates, and cell-based delivery systems. This theme will provide state-of-the-art information as to how drug delivery should be considered early in the drug development process and stimulate high-level discussion on next-generation drug delivery modalities. Discussion will also focus on biological mechanisms that enable state-of-the-art drug delivery platforms to be deployed for improved treatment of human disease.
Understand the nuances of advancing therapeutic discovery and development.
One of the many challenges in drug discovery and development is the ability to deliver a therapeutic to its site of action at effective concentrations.
Experience new modalities which have been designed to ensure successful cell/tissue drug delivery. Explore transporters and nucleic acid delivery vehicles.
Bag motivation through tough leads and excel state-of-the-art information on how drug delivery should be considered early in the drug development process.
The American Association of Pharmaceutical Scientists (AAPS) is a professional, scientific organization of approximately 9,000 members employed in academia, industry, government, and other research institutes worldwide. Founded in 1986, AAPS advances the capacity of pharmaceutical scientists to develop products and therapies that improve global health.
The American Association of Pharmaceutical Scientists (AAPS) is a professional scientific organization of approximately 9 000 members employed in academia industry government and other research institutes worldwide. Founded in 1986 AAPS advances the
The American Association of Pharmaceutical Scientists (AAPS) is a professional scientific organization of approximately 9 000 members employed in academia industry government and other research institutes worldwide. Founded in 1986 AAPS advances the capacity of pharmaceutical scientists to develop p
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